Moffitt Cancer Center Moffitt Cancer Center’s efforts to increase minority accrual to cancer treatment trials got a boost from the National Cancer Institute’s Connecting Underrepresented Populations to Clinical Trials U01 Grants Program. The five-year, $3.7 million grant will help the cancer center develop new digital tools and community outreach strategies to reach Black and Hispanic cancer patients and physicians in the Tampa Bay community. Read More

Winship Cancer Institute of Emory University A $1.34 million Science Education Partnership Award from the National Institutes of Health will help Winship Cancer Institute scientists investigate whether problem-based learning, directly applied to case studies relevant to communities in Georgia, will more effectively help to increase diversity in the biomedical research workforce and reduce health disparities. Read More

The University of Kansas Cancer Center Shellie Ellis, PhD, has been awarded a $1.2 million R01 grant from the National Cancer Institute (NCI) to test an intervention she and her colleagues designed known as TEAMSPORT (Multi-TEAM Systems Framework Precision Oncology Reflex Testing). The goal is to create a standardized approach to the ordering of genomic tests and adapt it for use in community cancer centers. Read More

University of Michigan Rogel Cancer Center A dietary change could be a key to enhancing colon cancer treatment, a study from the University of Michigan Rogel Cancer Center finds. One of the most important nutrient sensing molecules in a cell is called mTORC1. While mTORC1 is known to be hyperactive in colon cancer, the key question is whether colon tumors hijack nutrient sensing pathways to fire up the master regulator. Read More

Vanderbilt-Ingram Cancer Center Cribriform prostate cancer is an aggressive subtype of the disease characterized by its histology, but little is known about its molecular pathways. Research from Vanderbilt-Ingram Cancer Center has revealed new information about these pathways, including potential therapies. Read More

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University A novel artificial intelligence blood testing technology developed and used by Johns Hopkins Kimmel Cancer Center researchers to successfully detect lung cancer in a 2021 study has now detected more than 80 percent of liver cancers in a new study of 724 people. Read More

Winship Cancer Institute of Emory University A targeted therapy for children with high-risk Hodgkin lymphoma was shown to significantly reduce relapse rates when tested in a large multicenter clinical trial conducted by the Children’s Oncology Group and led by pediatric oncologists at Winship Cancer Institute of Emory University, Children’s Healthcare of Atlanta and Roswell Park Comprehensive Cancer Center. Read More

University of Michigan Rogel Cancer Center Researchers at the University of Michigan Rogel Cancer Center have identified a novel treatment approach to an aggressive type of pediatric brain cancer, using therapies already approved to treat cancer. Read More

Vanderbilt-Ingram Cancer Center Myocarditis can occur in cancer patients treated with immune checkpoint inhibitors. Although the adverse event is rare, the mortality rate is nearly 50 percent. Now, researchers from Vanderbilt-Ingram Cancer Center have identified the mechanism for the deadly heart inflammation. Read More

Cedars-Sinai Cancer Investigators from Cedars-Sinai Cancer have identified an investigational therapeutic approach that could be effective against treatment-resistant prostate cancer. Results of their Phase II clinical trial have led to a larger, multicenter trial that will soon be underway. Read More

Sylvester Comprehensive Cancer Center, University of Miami Physician scientists at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine have published a review that clarifies current treatment approaches for myelodysplastic syndromes. Read More

Laura and Isaac Perlmutter Cancer Center at NYU Langone The recent development of drugs that can kill cancer cells with KRAS mutations has been a major breakthrough. But in nearly all patients, tumors eventually become resistant to these drugs, and they stop working. Two research teams have now developed a way to overcome this resistance that may enable KRAS-targeted drugs—and perhaps drugs that target other mutant cancer-causing proteins in cancer cells—to pull double duty as an immunot…

The University of Texas MD Anderson Cancer Center A team of researchers at The University of Texas MD Anderson Cancer Center has developed a nanotechnology platform that can change the way the immune system sees solid tumor cells, making them more receptive to immunotherapy. The preclinical findings suggest this adaptable immune conversion approach has the potential for broad application across many cancer types. Read More

Roswell Park Comprehensive Cancer Center Researchers from Roswell Park Comprehensive Cancer Center, in collaboration with Gero and Genome Protection Inc., recently published new work that demonstrates the power of artificial intelligence (AI) combined with analytical tools borrowed from the physics of complex systems to provide insights into the nature of aging, resilience, and future medical interventions for age-related diseases including cancer. Read More

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University In a small study, researchers at the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy have successfully trained a machine learning algorithm to predict, in hindsight, which patients with melanoma would respond to treatment and which would not respond. Read More

The Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute The new Lung Nodule Program at The Ohio State University Comprehensive Cancer Center – The James combines the benefits of automated natural language processing tools with a subspecialized treatment team to create a system for flagging and methodically evaluating incidental lung nodule findings to capture subtle signs of lung cancer. Read More